코로나바이러스(SARS-CoV-2)에 대한 구강 양치액의 효과: 주제 범위 문헌고찰
A scoping review on the effectiveness of mouth rinse against SARS-CoV-2
이주영, 김효정, 정회인, 김백일,
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이주영 ( Lee Joo-Young ) - Yonsei University College of Dentistry Department of Preventive Dentistry & Public Oral Health
김효정 ( Kim Hyo-Jung ) - Yonsei University College of Dentistry Department of Preventive Dentistry & Public Oral Health
정회인 ( Jung Hoi-In ) - Yonsei University College of Dentistry Department of Preventive Dentistry & Public Oral Health
김백일 ( Kim Baek-Il ) - Yonsei University College of Dentistry Department of Preventive Dentistry & Public Oral Health
Abstract
Although studies reporting the efficacy of mouth rinse against SARS-CoV-2 have been continuously published, it is challenging to select literature through qualitative meta-synthesis or quality assessment of the study. Therefore, this study aims to systematically review the efficacy of mouth rinse against SARS-CoV-2 using the scoping review method and to provide the latest information.
Literature search on electronic databases (PubMed, Scopus, and Cochrane Trials) was conducted. After establishing literature inclusion and exclusion criteria, two independent researchers were selected literatures. Of the 15 articles were included in this scoping review, 11 were in vitro studies, and four were in vivo studies.
The ingredients tested in these studies were povidone-iodine, chlorhexidine, hydrogen peroxide, essential oils, and quaternary ammonium compounds, and they showed various efficacy against SARS-CoV-2.
Despite the relatively limited evidence from the included studies, the use of mouth rinse has the potential to reduce the viral load of SARS-CoV-2. In particular, povidone-iodine is expected to be the most effective against SARS-CoV-2, given the evidence so far.
키워드
COVID-19; mouth rinse; povidone-iodine; SARS-CoV-2; virus
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